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United States and Japanese scientists have identified a key step in metabolic pathways associated with diabetes and cancer. The study on activation of the protein complex TORC 2 was published online in the journal Current Biology Oct. 28. TORC 2 activates a protein called Akt, which plays a crucial role in how cells respond to insulin, said Kazuo Shiozaki, professor of microbiology in the College ...

Two transporters that deliver alternative energy sources to the eye may help delay retinal damage that can occur in diabetes, scientists say. The transporters, SMCT1 and SMCT2, can circumvent the eye's protective blood-retinal barrier, delivering energy sources lactate and ketone bodies to a healthy eye, says Dr. Pamela Martin, biochemist at the Medical College of Georgia........

La Jolla, CA With the help of genetically engineered mice whose livers turned into glowing light bulbs, scientists at the Salk Institute for Biological Studies have illuminated the underpinnings of an insidious and growing health concern type II diabetes. In the study reported in the September 5 advanced online edition of Nature, the scientists report that a protein called TORC2 serves as a key bi...